BDBM759127 2-(3-(5-Amino-6-(2-methylthiazol-5-yl)pyrazin- 2-yl)-4-methvlphenyl)-3,3,3-trifluoropropane- 1,2-diol trifluoroacetate salt (single enantiomer isolated, believed to be (S)-2-(3-(5-Amino-6-(2- methylthiazol-5-yl)pyrazin-2-yl)-4- methylphenyl)-3,3,3-trifluoropropane-1,2-diol)::US12365668, Example 10

SMILES Cc1ccc(C(O)(CO)C(F)(F)F)cc1c3cnc(N)c(c2cnc(C)s2)n3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759127   

LigandPNGBDBM759127(2-(3-(5-Amino-6-(2-methylthiazol-5-yl)pyrazin- 2-y...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759127(2-(3-(5-Amino-6-(2-methylthiazol-5-yl)pyrazin- 2-y...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent