BDBM759154 US12365685, Example T-10

SMILES Cn5cc(c4cnc3c(c2ccc(CC(=O)Nc1cc(C(C)(C)C(F)(F)F)on1)cc2)cnn3c4)cn5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759154   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen TargetRx

US Patent
LigandPNGBDBM759154(US12365685, Example T-10)
Affinity DataIC50: 0.100nMAssay Description:Reagents and MaterialsRet wt (Carna, Cat. No. 08-159-10 ug), RET (V804M), Active (Signalchem, Cat. No. R02-12GG), HTRF KinEASE-TK kit (Cisbio, Cat. N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen TargetRx

US Patent
LigandPNGBDBM759154(US12365685, Example T-10)
Affinity DataIC50: 0.230nMAssay Description:Reagents and MaterialsRet wt (Carna, Cat. No. 08-159-10 ug), RET (V804M), Active (Signalchem, Cat. No. R02-12GG), HTRF KinEASE-TK kit (Cisbio, Cat. N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent