BDBM759163 3-Amino-N-((1S,2S)-2- hydroxycyclohexyl)-6-(2-(methyl-d3)-5- ((S)-1,1,1-trifluoro-2,3-dihydroxypropan-2- yl)phenyl)pyrazine-2-carboxamide, trifluoroacetate salt (single enantiomer)::US12365668, Example 27

SMILES [2H]C([2H])([2H])c1ccc([C@](O)(CO)C(F)(F)F)cc1c3cnc(N)c(C(=O)N[C@H]2CCCC[C@@H]2O)n3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759163   

LigandPNGBDBM759163(3-Amino-N-((1S,2S)-2- hydroxycyclohexyl)-6-(2-(met...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759163(3-Amino-N-((1S,2S)-2- hydroxycyclohexyl)-6-(2-(met...)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent