BDBM759167 (S)-3-Amino-N-(4- (hydroxymethyl)bicyclo[2.1.l]hexan-1-yl)- 6-(2-(methyl-d3)-5-(1,1,1-trifluoro-2,3- dihydroxypropan-2-yl)phenyl)pyrazine-2- carboxamide (single enantiomer)::US12365668, Example 31

SMILES [2H]C([2H])([2H])c1ccc([C@](O)(CO)C(F)(F)F)cc1c4cnc(N)c(C(=O)NC23CCC(CO)(C2)C3)n4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759167   

LigandPNGBDBM759167((S)-3-Amino-N-(4- (hydroxymethyl)bicyclo[2.1.l]hex...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759167((S)-3-Amino-N-(4- (hydroxymethyl)bicyclo[2.1.l]hex...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent