BDBM759186 (8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-2-yl)methanol::US12365687, Example 4

SMILES OCc1cn2c(n1)CN=C(c1c(F)cccc1F)c1c-2ccc(Br)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 759186   

LigandPNGBDBM759186((8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-benzo[...)
Affinity DataKi:  1.14nMAssay Description:Table 1 and 3: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Fluma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759186((8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-benzo[...)
Affinity DataKi:  8.80nMAssay Description:Table 1 and 3: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Fluma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759186((8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-benzo[...)
Affinity DataKi:  8.80nMAssay Description:Table 2: Electrophysiological experiments were performed using the Roboocyte instrument (MultiChannelSystems, Reutlingen, Germany) on days 3 to 5 aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759186((8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-benzo[...)
Affinity DataKi:  216nMAssay Description:Table 1 and 3: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Fluma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent