BDBM759430 8-(1,1-difluoro-5- azaspiro[2.4]heptan- 5-yl)-6-methyl-N-(1- (methylsulfonyl) piperidin-4- yl)pyrido[3,4- d]pyrimidin- 2-amine::US20250235456, Compound 41

SMILES Cc1cc2cnc(NC3CCN(S(C)(=O)=O)CC3)nc2c(N2CCC3(C2)CC3(F)F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 759430   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Iambic Therapeutics

US Patent
LigandPNGBDBM759430(8-(1,1-difluoro-5- azaspiro[2.4]heptan- 5-yl)-6-me...)
Affinity DataIC50: 200nMAssay Description:The purpose of CDK1/Cyclin Bi assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM759430(8-(1,1-difluoro-5- azaspiro[2.4]heptan- 5-yl)-6-me...)
Affinity DataIC50: 200nMAssay Description:The purpose of CDK2/Cyclin El assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM759430(8-(1,1-difluoro-5- azaspiro[2.4]heptan- 5-yl)-6-me...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent