BDBM760144 (3R)-3-amino-5-[(4-chlorophenyl)methyl]-8-fluoro-7-(5-methoxy-3-pyridyl)-1,1-dioxo-2,3-dihydro-1%6,5-benzothiazepin-4-one::US20250236617, Example 26

SMILES COc1cncc(-c2cc3c(cc2F)S(=O)(=O)C[C@H](N)C(=O)N3Cc2ccc(Cl)cc2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 760144   

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760144((3R)-3-amino-5-[(4-chlorophenyl)methyl]-8-fluoro-7...)
Affinity DataIC50: 5.32E+3nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760144((3R)-3-amino-5-[(4-chlorophenyl)methyl]-8-fluoro-7...)
Affinity DataIC50: 5.72E+4nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent