BDBM760145 (3R)-3-amino-7-(5-chloro-3-pyridyl)-8-fluoro-5-[[4-(4-methoxyphenyl)phenyl]methyl]-1,1-dioxo-2,3-dihydro-1λ6,5-benzothiazepin-4-one::US20250236617, Example 27

SMILES COc1ccc(-c2ccc(CN3C(=O)[C@@H](N)CS(=O)(=O)c4cc(F)c(-c5cncc(Cl)c5)cc43)cc2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 760145   

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760145((3R)-3-amino-7-(5-chloro-3-pyridyl)-8-fluoro-5-[[4...)
Affinity DataIC50: 6.50E+3nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760145((3R)-3-amino-7-(5-chloro-3-pyridyl)-8-fluoro-5-[[4...)
Affinity DataIC50: 4.12E+4nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent