BDBM760154 (3R)-3-amino-8-fluoro-1,1-dioxo-7(3R)-3-amino-7-(3-tert-butyl-1,2,4-triazin-5-yl)-8-fluoro-1,1-dioxo-5-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-2,3-dihydro-1λ6,5-benzothiazepin-4-one::US20250236617, Example 36

SMILES CC(C)(C)c1nncc(-c2cc3c(cc2F)S(=O)(=O)C[C@H](N)C(=O)N3Cc2ccc(-c3noc(C(F)(F)F)n3)cc2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 760154   

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760154((3R)-3-amino-8-fluoro-1,1-dioxo-7(3R)-3-amino-7-(3...)
Affinity DataIC50: 1.50E+3nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM760154((3R)-3-amino-8-fluoro-1,1-dioxo-7(3R)-3-amino-7-(3...)
Affinity DataIC50: 2.45E+4nMAssay Description:First Table: A concentrated liposome solution was prepared in assay buffer without DTT and BSA: 2 mM of DLG in 21 mM of total liposome (2 mM DLG/8 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent