BDBM760161 US20250236619, Compound I-14

SMILES [2H]C([2H])([2H])N(CC1=NC(Nc2cnc(-c3ccnc4c3c3c(n4C)CCC3)c3c2C(=O)NC3)=CCC1C1CCOCC1)C([2H])([2H])[2H]

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 760161   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM760161(US20250236619, Compound I-14)
Affinity DataIC50: 1.40nMAssay Description:A kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. A 100 ng/μL HPK1 (Life technology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent