BDBM760163 US20250236619, Compound I-16

SMILES [2H]C([2H])(c1nc(Nc2ccc(-c3ccnc4c3c3c(n4C)CCC3)c3c2C(=O)NC3)ccc1C1CCOCC1)N(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 760163   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM760163(US20250236619, Compound I-16)
Affinity DataIC50: 2.10nMAssay Description:A kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. A 100 ng/μL HPK1 (Life technology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent