BDBM760211 US20250236619, Compound I-74

SMILES CN(C)Cc1nc(Nc2ccc(C3=C4C5=C(C=CC4N=C3)OCC5)c3c2C(=O)NC3)ccc1C1CCN(C)C(=O)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 760211   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM760211(US20250236619, Compound I-74)
Affinity DataIC50: 3.40nMAssay Description:A kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. A 100 ng/μL HPK1 (Life technology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent