BDBM760384 N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3- fluorophenyl]-1-ethyl-5-(4- fluorophenyl)-6-methyl-4-oxopyridine- 3-carboxamide::US12371428, Compound 63
SMILES CCn5cc(C(=O)Nc3ccc(Oc1ccnc2cc(OC)c(OC)nc12)c(F)c3)c(=O)c(c4ccc(F)cc4)c5C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 760384
Affinity DataIC50: 100nMAssay Description:Example A-1: Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKSRGDYMTMQIG (SEQ ID NO:1), 1...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example B-1: Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesiu...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example D-1: Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKKGQEEEYVFIE (SE...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example C-1: Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIY...More data for this Ligand-Target Pair