BDBM760716 N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3- fluorophenyl]-5-(4-fluorophenyl)-4,6- dihydroxy-2-methylpyridine-3- carboxamide::US12371428, Compound 443
SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)nc(O)c(-c5ccc(F)cc5)c4O)cc3F)c2nc1OC
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 760716
Affinity DataIC50: 100nMAssay Description:Example B-1: Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesiu...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example D-1: Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKKGQEEEYVFIE (SE...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example C-1: Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIY...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example A-1: Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKSRGDYMTMQIG (SEQ ID NO:1), 1...More data for this Ligand-Target Pair