BDBM761234 US20250243180, Compound 226

SMILES Cc1nnc(C2(C(=O)NCc3cc(Cl)c(C4CCC(=O)NC4=O)c(Cl)c3)CCC2)o1

InChI Key InChIKey=CRDFMOPYLXLCGX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761234   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 761234BDBM761234(US20250243180, Compound 226)
Affinity DataEC50:  130nMAssay Description:A one pot detection solution of CRBN-DDB1 (2.5 nM), Anti-His Terbium Cryptate Gold (1×, PerkinElmer Cat. #: 61HI2TLB), and Cy5-Thalidomide (100 nM, T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 761234BDBM761234(US20250243180, Compound 226)
Affinity DataEC50:  550nMAssay Description:A one pot detection solution of CRBN-DDB1 (2.5 nM), Anti-His Terbium Cryptate Gold (1×, PerkinElmer Cat. #: 61HI2TLB), and Cy5-Thalidomide (100 nM, T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent