BDBM761316 CHEM-US-00368 4-(5-(difluoromethyl)-2-((5- methoxy-7-methyl-1H-indol-4- yl)methyl)octahydrocyclopenta [c]pyrrol-1-yl)benzoic acid::US20250243186, Example 39

SMILES COc1cc(C(=O)O)c2[nH]ccc2c1CN1CC2CC(C(F)F)CC2C1c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 761316   

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761316(CHEM-US-00368 4-(5-(difluoromethyl)-2-((5- methoxy...)
Affinity DataIC50: 2.60nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761316(CHEM-US-00368 4-(5-(difluoromethyl)-2-((5- methoxy...)
Affinity DataIC50: 7.30nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761316(CHEM-US-00368 4-(5-(difluoromethyl)-2-((5- methoxy...)
Affinity DataIC50: 7.30nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent