BDBM761338 5-(7-Chloro-4-(dimethylamino)-2-oxoquinazolin-1(2H)-yl)-N-(3-(7-chloro-4-(dimethylamino)-2-oxoquinazolin-1(2H)-yl)phenyl)-4-methylthiophene-3-carboxamide::US20250243188, Example 3

SMILES Cc1c(C(=O)Nc2cccc(-n3c(=O)nc(N(C)C)c4ccc(Cl)cc43)c2)csc1-n1c(=O)nc(N(C)C)c2ccc(Cl)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 761338   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM761338(5-(7-Chloro-4-(dimethylamino)-2-oxoquinazolin-1(2H...)
Affinity DataIC50: 200nMAssay Description:For the assay, a mixture of 1 mM L-methionine/1 mM ATP (2× final pre-stopped concentration) in assay buffer; MAT2A (2× final pre-stopped concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent