BDBM761342 5-(2,4-Dioxo-7-(trifluoromethyl)-3,4-dihydroquinazolin-1(2H)-yl)-N-(3-(2,4-dioxo-7-(trifluoromethyl)-3,4-dihydroquinazolin-1(2H)-yl)phenyl)thiophene-3-carboxamide::US20250243188, Example 5

SMILES O=C(Nc1cccc(-n2c(=O)[nH]c(=O)c3ccc(C(F)(F)F)cc32)c1)c1csc(-n2c(=O)[nH]c(=O)c3ccc(C(F)(F)F)cc32)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 761342   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM761342(5-(2,4-Dioxo-7-(trifluoromethyl)-3,4-dihydroquinaz...)
Affinity DataIC50: 200nMAssay Description:For the assay, a mixture of 1 mM L-methionine/1 mM ATP (2× final pre-stopped concentration) in assay buffer; MAT2A (2× final pre-stopped concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
11/12/2025
Entry Details
US Patent