BDBM761346 5-(7-Chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)-N-(3-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)phenyl)-1-methyl-1H-imidazole-2-carboxamide::US20250243188, Example 9

SMILES Cn1c(-n2c(=O)[nH]c(=O)c3ccc(Cl)cc32)cnc1C(=O)Nc1cccc(-n2c(=O)[nH]c(=O)c3ccc(Cl)cc32)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 761346   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM761346(5-(7-Chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-...)
Affinity DataIC50: 200nMAssay Description:For the assay, a mixture of 1 mM L-methionine/1 mM ATP (2× final pre-stopped concentration) in assay buffer; MAT2A (2× final pre-stopped concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent