BDBM761348 7-Chloro-1-(4-(((3-(7-chloro-4-(dimethylamino)-2-oxoquinazolin-1(2H)-yl)phenyl)amino)methyl)thiophen-2-yl)-4-(dimethylamino)quinazolin-2(1H)-one::US20250243188, Example 11

SMILES CN(C)c5nc(=O)n(c4cccc(NCc3csc(n2c(=O)nc(N(C)C)c1ccc(Cl)cc12)c3)c4)c6cc(Cl)ccc56

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 761348   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM761348(7-Chloro-1-(4-(((3-(7-chloro-4-(dimethylamino)-2-o...)
Affinity DataIC50: 200nMAssay Description:For the assay, a mixture of 1 mM L-methionine/1 mM ATP (2× final pre-stopped concentration) in assay buffer; MAT2A (2× final pre-stopped concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent