BDBM761418 N-[4-(3-Cyanophenyl)-5-(7-methyl-1H-indazol-5-yl)thiazol-2-yl]-2-oxa-6-azaspiro[3.3]heptane-6-carboxamide::US20250243194, Example 27

SMILES Cc1cc(-c2sc(NC(=O)N3CC4(COC4)C3)nc2-c2cccc(C#N)c2)cc2cn[nH]c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 761418   

TargetAdenosine receptor A2a(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761418(N-[4-(3-Cyanophenyl)-5-(7-methyl-1H-indazol-5-yl)t...)
Affinity DataKi:  0.0800nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761418(N-[4-(3-Cyanophenyl)-5-(7-methyl-1H-indazol-5-yl)t...)
Affinity DataKi:  0.5nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761418(N-[4-(3-Cyanophenyl)-5-(7-methyl-1H-indazol-5-yl)t...)
Affinity DataKi:  2.90nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761418(N-[4-(3-Cyanophenyl)-5-(7-methyl-1H-indazol-5-yl)t...)
Affinity DataKi:  907nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent