BDBM761472 N-(4-(2-(4- chlorophenyl)- 1- methoxypropan- 2-yl)thiazol-2- yl)-2,6- difluoro-4- (piperazin-1-::US20250241908, Compound C029::US20250381196, Compound C029

SMILES COCC(C)(c1ccc(Cl)cc1)c4csc(NC(=O)c3c(F)cc(N2CCNCC2)cc3F)n4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 761472   

TargetAlpha-protein kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 761472BDBM761472(N-(4-(2-(4- chlorophenyl)- 1- methoxypropan- 2-yl)...)
Affinity DataIC50: 16nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 761472BDBM761472(N-(4-(2-(4- chlorophenyl)- 1- methoxypropan- 2-yl)...)
Affinity DataIC50: 128nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 761472BDBM761472(N-(4-(2-(4- chlorophenyl)- 1- methoxypropan- 2-yl)...)
Affinity DataIC50: 128nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent