BDBM761612 US20250243219, Compound 57

SMILES C[C@@H]1NC(=O)[C@H](C[C@@H]2CCCNC2)OC(=O)C(C)(C)/C=C/c2ccc3ccc(nc3c2)N(C)NC(=O)[C@@H]2CCCN(N2)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761612   

LigandPNGBDBM761612(US20250243219, Compound 57)
Affinity DataIC50: 7.60nMAssay Description:Cyclophilins are enzymes that catalyse the cis-trans isomerisation of peptide bonds to the amino acid proline. This event is important in many biolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/13/2025
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Cypralis

US Patent
LigandPNGBDBM761612(US20250243219, Compound 57)
Affinity DataIC50: 7.80nMAssay Description:Cyclophilins are enzymes that catalyse the cis-trans isomerisation of peptide bonds to the amino acid proline. This event is important in many biolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/13/2025
Entry Details
US Patent