BDBM761651 2-(3-fluorophenyl)-2-(2-(4-(4- methylpiperazin-1-yl)phenyl)- 7-oxo-5,7-dihydro-6H-pyrrolo- [3,4-b]pyridin-6-yl)-N-(thiazol- 2-yl)acetamide::US12377080, Compound 14

SMILES CN1CCN(c2ccc(-c3ccc4c(n3)C(=O)N(C(C(=O)Nc3nccs3)c3cccc(F)c3)C4)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761651   

LigandPNGBDBM761651(2-(3-fluorophenyl)-2-(2-(4-(4- methylpiperazin-1-y...)
Affinity DataIC50: 4nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM761651(2-(3-fluorophenyl)-2-(2-(4-(4- methylpiperazin-1-y...)
Affinity DataIC50: 32nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent