BDBM761657 2-(2-(3-fluoro-4-(1-methyl- piperidin-4-yl)phenyl)-7-oxo- 5,7-dihydro-6H-pyrrolo[3,4- b]pyridin-6-yl)-2-(3-fluoro- phenyl)-N-(thiazol-2-yl)- acetamide::US12377080, Compound 20

SMILES CN1CCC(c2ccc(-c3ccc4c(n3)C(=O)N(C(C(=O)Nc3nccs3)c3cccc(F)c3)C4)cc2F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761657   

LigandPNGBDBM761657(2-(2-(3-fluoro-4-(1-methyl- piperidin-4-yl)phenyl)...)
Affinity DataIC50: 1nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM761657(2-(2-(3-fluoro-4-(1-methyl- piperidin-4-yl)phenyl)...)
Affinity DataIC50: 5nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent