BDBM761659 2-(5-fluoro-2-hydroxyphenyl)- 2-(3-(4-(1-methylpiperidin-4- yl)phenyl)-5-oxo-5,7-dihydro- 6H-pyrrolo[3,4-b]pyridin-6-yl)- N-(pyridin-2-yl)acetamide::US12377080, Compound 22

SMILES CN1CCC(c2ccc(-c3cnc4c(c3)C(=O)N(C(C(=O)Nc3ccccn3)c3cc(F)ccc3O)C4)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761659   

LigandPNGBDBM761659(2-(5-fluoro-2-hydroxyphenyl)- 2-(3-(4-(1-methylpip...)
Affinity DataIC50: 1nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM761659(2-(5-fluoro-2-hydroxyphenyl)- 2-(3-(4-(1-methylpip...)
Affinity DataIC50: 5nMAssay Description:EGFR biochemical activity measurements were carried out using the homogeneous time-resolved fluorescence (HTRF) assay (Cisbio). Inhibitors and DMSO n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent