BDBM761662 US12377152, Compound 166099

SMILES O=C1CCC(N2Cc3cc(OCCCC(=O)Nc4ccc(-c5ccc(-c6cc7ccncc7[nH]6)cc5)cn4)ccc3C2=O)C(=O)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761662   

TargetAlpha-synuclein(Human)
Aprinoia Therapeutics

US Patent
LigandPNGBDBM761662(US12377152, Compound 166099)
Affinity DataKd:  40nMAssay Description:PBB5 competition assay: 2 μM of α-synuclein was incubated with 0.26 μM 2-(4-(2-(methylamino)pyridine-5-yl)-1,3-butadiene-1-yl)benzothiazole-6-ol (PBB...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetAlpha-synuclein(Human)
Aprinoia Therapeutics

US Patent
LigandPNGBDBM761662(US12377152, Compound 166099)
Affinity DataKd:  5.63E+3nMAssay Description:(A) Expression and purification of recombinant wild-type human α-synuclein: 0.5 mM IPTG was used to induce production of wild type human α-synuclein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent