BDBM761674 US12377152, Compound 166124

SMILES CN(C)c1ccc(-c2ccc(-c3nc4ccc(C(=O)OCCOCCOCCOc5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)cc4s3)cc2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761674   

TargetAlpha-synuclein(Human)
Aprinoia Therapeutics

US Patent
LigandPNGBDBM761674(US12377152, Compound 166124)
Affinity DataKd:  30nMAssay Description:PBB5 competition assay: 2 μM of α-synuclein was incubated with 0.26 μM 2-(4-(2-(methylamino)pyridine-5-yl)-1,3-butadiene-1-yl)benzothiazole-6-ol (PBB...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetAlpha-synuclein(Human)
Aprinoia Therapeutics

US Patent
LigandPNGBDBM761674(US12377152, Compound 166124)
Affinity DataKd:  340nMAssay Description:(A) Expression and purification of recombinant wild-type human α-synuclein: 0.5 mM IPTG was used to induce production of wild type human α-synuclein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent