BDBM761675 US12377086, Compound 43

SMILES O=C(O)c1cnc2c(O)cccc2c1

InChI Key

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 761675   

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataKi:  490nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataKi:  530nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataIC50: 1.60E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataIC50: 1.90E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent