BDBM762281 US12378224, Example 581

SMILES Nc1ncc(-c2ccnc(N3CCNCC3)c2)cc1C(=O)N[C@@H]1CCN(C(=O)c2ccc(-c3ccc(F)cc3Cl)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762281   

LigandPNGBDBM762281(US12378224, Example 581)
Affinity DataIC50: 10nMAssay Description:Table 3: For the SAR (structure-activity relationship) and compound screening, HTRF (Homogeneous Time Resolved Fluorescence) kinase activity assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent