BDBM762458 US12378231, Example 77

SMILES C=COc1ccc(N(c2ccc(F)cc2)C2CCN(C(=O)n3nnc4cc(C#N)ccc43)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 762458   

TargetMonoglyceride lipase(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762458(US12378231, Example 77)
Affinity DataIC50: 5.5nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762458(US12378231, Example 77)
Affinity DataIC50: 550nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent