BDBM762476 US12378231, Example 95

SMILES COc1cccc(C(c2cccc(OC)c2)N2CCN(C(=O)n3nnc4ccc(C#N)cc43)CC2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 762476   

TargetMonoglyceride lipase(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762476(US12378231, Example 95)
Affinity DataIC50: 5.5nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762476(US12378231, Example 95)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent