BDBM762514 US12378231, Example PF-04457845

SMILES O=C(Nc1cccnn1)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 762514   

TargetFatty-acid amide hydrolase 1(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762514(US12378231, Example PF-04457845)
Affinity DataIC50: 1.90nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Apogee Pharmaceuticals

US Patent
LigandPNGBDBM762514(US12378231, Example PF-04457845)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory effect of the test chemicals on activity of human recombinant FAAH was also studied for their selectivity using commercial FAAH inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent