BDBM762532 US12378241, Compound 9

SMILES Cn1cc(-c2ccn3c(-c4cc(CCC(C)(C)O)nc(-c5ccc(F)cc5F)c4)cnc3c2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 762532   

TargetVascular endothelial growth factor receptor 2(Human)
Cgenetech (Suzhou,China)

US Patent
LigandPNGBDBM762532(US12378241, Compound 9)
Affinity DataIC50: 3.73nMAssay Description:The IC50 value was determined using 33P isotope-labeled kinase activity test (Reaction Biology Corp) to evaluate the inhibitory ability of the compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Cgenetech (Suzhou,China)

US Patent
LigandPNGBDBM762532(US12378241, Compound 9)
Affinity DataIC50: 4.92nMAssay Description:The IC50 value was determined using 33P isotope-labeled kinase activity test (Reaction Biology Corp) to evaluate the inhibitory ability of the compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/17/2025
Entry Details
US Patent