BDBM762547 2-[[6-(5-amino-4-methyl-3-pyridyl)-7-fluoro-3- isoquinolyl]amino]-6-methyl-spiro[5,8- dihydropyrazolo[1,5-d][1,4]diazepine-4,1''- cyclopropane]-7-one::US12378249, Compound 111

SMILES Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762547   

LigandPNGBDBM762547(2-[[6-(5-amino-4-methyl-3-pyridyl)-7-fluoro-3- iso...)
Affinity DataKi:  0.0100nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/18/2025
Entry Details
US Patent