BDBM762722 US12378277, Compound WXD003

SMILES CS[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(O[C@@H]4CCN([C@@H]5CO[C@H](c6cc(F)ccc6F)[C@@H](N)C5)C4)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 762722   

LigandPNGBDBM762722(US12378277, Compound WXD003)
Affinity DataIC50: 2.90nMAssay Description:1) Experimental buffer: 10 mM 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES), 1.2 mM magnesium chloride (MgCl2), 4.7 mM potassium chloride (KCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)TBA
LigandPNGBDBM762722(US12378277, Compound WXD003)
Affinity DataIC50: 24.5nMAssay Description:The inhibitory activity of the compounds on recombinant human dipeptidyl peptidase 4 (rhDPP4) was evaluated by measuring the median inhibitory concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM762722(US12378277, Compound WXD003)
Affinity DataIC50: 44nMAssay Description:1) Experimental buffer: 10 mM 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES), 1.2 mM magnesium chloride (MgCl2), 4.7 mM potassium chloride (KCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent