BDBM762726 US12378277, Compound WXD007

SMILES CCc1ccc([C@@H]2O[C@H](SC)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(OC2CCN(C3CO[C@H](c4cc(F)ccc4F)[C@@H](N)C3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 762726   

TargetSodium/glucose cotransporter 2(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical

US Patent
LigandPNGBDBM762726(US12378277, Compound WXD007)
Affinity DataIC50: 1.44nMAssay Description:1) Experimental buffer: 10 mM 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES), 1.2 mM magnesium chloride (MgCl2), 4.7 mM potassium chloride (KCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/18/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical

US Patent
LigandPNGBDBM762726(US12378277, Compound WXD007)
Affinity DataIC50: 3.37nMAssay Description:1) Experimental buffer: 10 mM 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES), 1.2 mM magnesium chloride (MgCl2), 4.7 mM potassium chloride (KCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/18/2025
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical

US Patent
LigandPNGBDBM762726(US12378277, Compound WXD007)
Affinity DataIC50: 510nMAssay Description:The inhibitory activity of the compounds on recombinant human dipeptidyl peptidase 4 (rhDPP4) was evaluated by measuring the median inhibitory concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/18/2025
Entry Details
US Patent