BDBM762850 (S)-N-(1-cyano-2-(2-fluoro-4- (1''-(oxetan-3-yl)-3H- spiro[isobenzofuran-1,4''- piperidin]-6-yl)phenyl)ethyl)-3- (difluoromethyl)-1- methylazetidine-3-carboxamide::US20250250232, Example 39

SMILES CN1CC(C(=O)N[C@H](C#N)Cc2ccc(-c3ccc4c(c3)C3(CCN(C5COC5)CC3)OC4)cc2F)(C(F)F)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762850   

TargetDipeptidyl peptidase 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM762850((S)-N-(1-cyano-2-(2-fluoro-4- (1'-(oxetan-3-yl)-3H...)
Affinity DataIC50: 55nMAssay Description:Human DPP1 enzyme activity was determined by measuring release of the fluorophore aminomethyl coumarin (AMC) following enzymatic cleavage of the dipe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/21/2025
Entry Details
US Patent