BDBM762905 N-(4-(5-(4-Methyl-6-(3-(trifluoromethyl)pyrrolidin-1-yl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)-3-(6-azaspiro[2.5]octan-6-yl)phenyl)-2-hydroxyethane-1-sulfonamide::US20250250264, Compound I-104

SMILES Cc1cc(-c2nnc(-c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)o2)nc(N2CCC(C(F)(F)F)C2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762905   

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762905(N-(4-(5-(4-Methyl-6-(3-(trifluoromethyl)pyrrolidin...)
Affinity DataIC50: 13nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent