BDBM762908 N-(4-(4-(2-(Difluoromethyl)-6-(4,4-difluoropiperidin-1-yl)pyridin-4-yl)-1H-pyrazol-1-yl)-3-(6-azaspiro[2.5]octan-6-yl)phenyl)-2-hydroxyethane-1-sulfonamide::US20250250264, Compound I-107

SMILES O=S(=O)(CCO)Nc1ccc(-n2cc(-c3cc(C(F)F)nc(N4CCC(F)(F)CC4)c3)cn2)c(N2CCC3(CC2)CC3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762908   

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762908(N-(4-(4-(2-(Difluoromethyl)-6-(4,4-difluoropiperid...)
Affinity DataIC50: 8nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent