BDBM762913 N-(4-(4-(2-(6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-6-methylpyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(6-azaspiro[2.5]octan-6-yl)phenyl)-2-hydroxyethane-1-sulfonamide::US20250250264, Compound I-113

SMILES Cc1cc(-c2cnn(-c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)c2)nc(N2CC3C(C2)C3(F)F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762913   

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762913(N-(4-(4-(2-(6,6-Difluoro-3-azabicyclo[3.1.0]hexan-...)
Affinity DataIC50: 7nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent