BDBM762921 N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(4-methylpiperidin-1-yl)phenyl)-2-hydroxyethane-1-sulfonamide::US20250250264, Compound I-125

SMILES Cc1cc(-c2cnn(-c3ccc(NS(=O)(=O)CCO)cc3N3CCC(C)CC3)c2)nc(N2CCC(F)(F)CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762921   

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762921(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 5nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent