BDBM762957 WO2022060836, Compound A122 (page 70 of Table, 1a)::US20250250284, Example A122

SMILES CO[C@@H](C)c1ncc(N2CCN(C)CC2)cc1C1=C2CC(C)(C)COC(=O)[C@@H]3CCCN(N3)C(=O)[C@@H](NC(=O)[C@H]3C[C@@H]3C)Cc3nc(cs3)-c3ccc(c2c3)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 762957   

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 13nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 25nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 124nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent