BDBM763815 N-[4-(5-amino-1,3,4-thiadiazol- 2-yl)phenyl]-3-(4- fluorophenyl)pyrazin-2-amine::US12384772, Compound 1293

SMILES Nc1nnc(-c2ccc(Nc3nccnc3-c3ccc(F)cc3)cc2)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 763815   

TargetGlutaminyl-peptide cyclotransferase(Human)
Vivoryon Therapeutics

US Patent
LigandPNGBDBM763815(N-[4-(5-amino-1,3,4-thiadiazol- 2-yl)phenyl]-3-(4-...)
Affinity DataKi:  1.66E+3nMAssay Description:10 mM compound stock solutions were prepared in DMSO. For IC50 determination compound stocks were serially diluted (1:3) in DMSO.All measurements wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Vivoryon Therapeutics

US Patent
LigandPNGBDBM763815(N-[4-(5-amino-1,3,4-thiadiazol- 2-yl)phenyl]-3-(4-...)
Affinity DataKi:  6.89E+3nMAssay Description:10 mM compound stock solutions were prepared in DMSO. For IC50 determination compound stocks were serially diluted (1:3) in DMSO.All measurements wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent