BDBM764397 8-(4-(difluoromethyl)-2- (trifluoromethyl)phenyl)-9-(4-((1-(3- fluoropropyl)azetidin-3- ylidene)methyl)phenyl)-6,7-dihydro-5H- benzo[7]annulene-3-carboxylic acid::US20250255848, Example 51

SMILES O=C(O)c1ccc2c(c1)CCCC(c1ccc(C(F)F)cc1C(F)(F)F)=C2c1ccc(C=C2CN(CCCF)C2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 764397   

TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandPNGBDBM764397(8-(4-(difluoromethyl)-2- (trifluoromethyl)phenyl)-...)
Affinity DataIC50: 0.5nMAssay Description:MCF7 cells (ATCC) were seeded in 384 wells microplate (collagen coated) at a concentration of 10000 cells/30 μL per well in red phenol free MEM alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent