BDBM764431 US20250255868, Compound 10

SMILES C#Cc1cccc2cc(O)cc(-c3ncc4c(N5CC6CCC(C5)N6)nc(OCC56CCCN5CC(=C(F)F)C6)nc4c3F)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 764431   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM764431(US20250255868, Compound 10)
Affinity DataIC50: 15nMAssay Description:The positive inhibitor and test compounds (10 mM storage solution) were diluted by a 3-fold gradient with 100% DMSO. Transfer 2 μL diluted compound t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent