BDBM764434 US20250255868, Compound 22

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c(N5CCNC6(CC6)C5)nc(OC[C@@]56CCCN5C[C@H](F)C6)nc4c3F)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 764434   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM764434(US20250255868, Compound 22)
Affinity DataIC50: 15nMAssay Description:The positive inhibitor and test compounds (10 mM storage solution) were diluted by a 3-fold gradient with 100% DMSO. Transfer 2 μL diluted compound t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent