BDBM764538 US20250257051, Compound 49

SMILES CNC(=O)c1cnc(N2CC(C(=O)NC)C2)nc1Nc1cccc(-c2ncc(F)cn2)c1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 764538   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
1910 Genetics

US Patent
LigandPNGBDBM764538(US20250257051, Compound 49)
Affinity DataKd:  2.30nMAssay Description:Binding constants for compounds disclosed herein against the JH2 domain are determined by the following protocol for a KINOMEscan® assay (DiscoveRx)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent