BDBM764809 US20250257060, Compound 2

SMILES O=C(N[C@@H]1CCCC[C@H]1N1Cc2ccc(-c3nnc(C(F)F)o3)cc2S1(=O)=O)C(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 764809   

TargetHistone deacetylase 6(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.70nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 5(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetPolyamine deacetylase HDAC10(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 7(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Suzhou Genhouse Bio

US Patent
LigandPNGBDBM764809(US20250257060, Compound 2)
Affinity DataIC50: 5.00E+4nMAssay Description:HDAC proteins of different subtypes (purchased from BPS), test compounds, and substrate solutions at concentrations of 2.5-40 M (purchased from BPS) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent