BDBM764864 US20250257069, Compound MMT3-72-M2

SMILES Cc1cnc(Nc2ccc(OCCO)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 764864   

TargetTyrosine-protein kinase JAK1(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 2nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 16.3nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 55.2nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 701nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent